RNA Editing [electronic resource] / edited by H. Ulrich Gȵringer.

Editing Reactions from the Perspective of RNA Structure -- Editing of tRNA for Structure and Function -- RNA Editing by Adenosine Deaminases that Act on RNA (ADARs) -- Insertion/Deletion Editing in Physarum polycephalum -- RNA Editing in Plant Mitochondria -- RNA Editing in Chloroplasts -- Working Together: the RNA Editing Machinery in Trypanosoma brucei -- RNA Editing Accessory Factors the Example of mHel61p -- The Function of RNA Editing in Trypanosomes -- Evolutionary Aspects of RNA Editing.

The term "RNA editing" describes a diverse set of biochemical processes whereby genetic information is modulated on a post-transcriptional level i.e. on the level of ribonucleic acids (RNA). RNA editing has been demonstrated in viruses, protozoan organisms, in plants and in mammals and in many cases it has been identified as a key step in the regulation of gene expression. This book dedicates a chapter to each of the main types of RNA editing. All sections are written by experts in the various research areas and a specific focus is put on the correlation between RNA structure and function, as well as on the complex cellular machineries that catalyze the different editing reactions. This leads to a "state of the art" compendium of our current knowledge on RNA editing.

ZDB-2-SBL