Contrast Media [electronic resource] : Safety Issues and ESUR Guidelines / edited by Henrik S. Thomsen, Judith A. W. Webb.

General Issues -- Classification and Terminology -- Requests for Imaging Using Contrast Agents: What Information Must be Provided -- Off-Label Use of Medicines: Legal Aspects -- Pharmacovigilance: When to Report Adverse Reactions -- What is Required in Order to Get the Authorities to Approve a New Contrast Agent -- A Critical Review of Meta-Analysis of Adverse Events After Contrast Agents -- Iodinated and Gadolinium Contrast Media -- Prevention of Acute Reactions -- Management of Acute Adverse Reactions -- Contrast Medium-Induced Nephropathy -- Dialysis and Contrast Media -- Non-Insulin-Dependent Diabetes and Contrast Media -- Pregnancy and Lactation -- Phaeochromocytoma -- Interactions with Other Drugs and Clinical Tests -- Extravasation Injury -- Late Adverse Reactions -- Effects on the Blood and Endothelium -- Effect on Thyroid Function -- Pulmonary Effects -- MR Contrast Media -- Chelates and Stability -- Diagnostic Efficacy -- Radiography with Gadolinium Contrast Agents -- Acute Adverse Reactions -- Delayed Reactions: Nephrogenic Systemic Fibrosis -- Gadolinium-Based Contrast Agents -- Non-Gadolinium-Based Contrast Agents -- Safety of Ultrasonographic Agents -- Barium Preparations: Safety Issues -- ESUR Guidelines on Contrast Media -- Official Publications from the European Society of Urogenital Radiology.

In 1994 the European Society of Urogenital Radiology (ESUR) set up a committee to consider the safety of contrast media used for diagnostic imaging. Subsequently the committee questioned members, reviewed the literature, proposed guidelines and discussed these proposals with participants at the annual symposia of the society. The end result of this work was the successful first edition of this book, published in 2006. This second edition not only updates the previous edition, but also contains some completely new chapters, for example on gadolinium-based contrast agents, meta-analyses in contrast media research and various regulatory issues. Comprehensive consideration is given to the many different safety issues relating to iodinated, MR, ultrasound and barium contrast media. The text includes chapters on both acute and delayed non-renal adverse reactions and on renal adverse reactions. All those questions frequently raised in radiological practice are addressed, and the well-known ESUR guidelines on contrast media are included. This book, presented in a handy, easy to use format, provides an invaluable, unique and unparalleled source of information on the safety issues relating to contrast media.

ZDB-2-SME