Natural compounds as inducers of cell death [electronic resource] : volume 1 / edited by Marc Diederich, Karoline Noworyta.

Section 1, Phytochemicals as inducers of cell death mechanisms -- 1. Phytochemicals and Amino Acids: Inducers or Inhibitors of Cell Death? -- 2. Pomegranate-derived constituents as inducers of cell death: implications in cancer prevention and therapy -- 3. Antitumor effects of anthocyanins: focus on apoptosis -- 4. Anti-proliferative and apoptosis-inducing properties of Xanthohumol, a prenylated chalcone from hops (Humulus lupulus L.) -- 5. Bioavailabitility and Metabolism of Curcuminoids. Section 2, Natural compounds from animal origins -- 6. Melatonin in cell fate decisions: mechanistic perspectives and therapeutical potential -- 7. Pharmacologically active compounds from ticks and other arthropods and their potential use in anticancer therapy. Section 3, Polyphenols as inducers of cell death -- 8. Induction of Apoptosis by Polyphenolic Compounds in Cancer Cells -- 9. Encapsulation of natural polyphenols with antioxidant properties in polyelectrolyte capsules and nanoparticles -- 10. Induction of Cell Death Occurring with Autophagy by Polyphenolic Compounds in Cancer -- Section 4, Redox active natural compounds -- 11. Total antioxidant capacity: a useful tool in assessing antioxidant intake status -- 12. Natural sulfur products as redox modulators and selective inducers of cell death -- 13. Diallyl sulfides and the decision about life and death of a cell -- Section 5, Effect of natural compounds on cell cell signaling pathways -- 14. Natural compounds as specific inhibitors of cyclin-dependent kinases past, present and future -- 15. Plant-derived isoprenoids mediate regulation of mTOR signaling in tumor cells -- 16. Regulation of MicroRNAs by Natural Compounds: Implications for Cancer Therapy -- Section 6, Phytochemicals in inflammation and cancer -- 17. Interference with estrogen receptor- by dietary components: impact on the balance between cell proliferation and cell death -- 18. Natural Triterpenoids from Olive Oil: Potential Activities Against Cancer -- 19. Dietary sources of natural inducers of cell death: considerations for cancer therapy and prevention -- Section 7, Phytochemicals in health and disease -- 20. Tocotrienols in the control of pathological fibroinflammatory processes -- 21. Anthocyanins: Janus nutraceuticals displaying chemotherapeutic and neuroprotective properties -- Index.

The content of this book gives a multi-disciplinary approach into the anti-cancer research field related to natural products and dietary compounds. Mainly, it covers the area of antitumor activity through an in-depth description of the cytotoxic, anti-inflammatory and anti-oxidant properties in cancer, inflammatory and cardio-vascular diseases. The cell death inducing mechanisms (apoptosis, anti-proliferative activity, angiogenesis, cell cycle control, cytostatic property and autophagy) give an overview of how natural products are able to target cancer cells.