Cysteine Proteases of Pathogenic Organisms [electronic resource] / edited by Mark W. Robinson, John P. Dalton.

Papa InLike Proteases Of Staphylococcus Aureus -- The LysineSpecific Gingipain Of Porphyromonas: Importance To Pathogenicity -- Falcipains And Other Cysteine Proteases Of Malaria Parasites -- Cathepsin Proteases In Toxoplasma Gondii -- Entamoeba Histolytica CathepsinLike Enzymes -- Cysteine Peptidases Of Kinetoplastid Parasites -- Cruzain: The Path From Target Validation To The Clinic -- The Phylogeny, Structure And Function Of Trematode Cysteine Proteases, With Particular Emphasis On The Fasciola Hepatica Cathepsin L Family -- Cathepsins B1 And B2 Of Trichobilharzia Spp., Bird Schistosomes Causing Cercarial Dermatitis -- Proteases In BloodFeeding Nematodes And Their Potential As Vaccine Candidates -- Cysteine Proteases From Bloodfeeding Arthropod Ectoparasites -- How PathogenDerived Cysteine Proteases Modulate Host Immune Responses -- Cystatins Of Parasitic Organisms.

Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structurefunction relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research.

ZDB-2-SBL